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T*
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T*
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T*
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T*
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T*
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T*
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T*
-0.004 Tc
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/F1 1 Tf
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0 Tc
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173.9 685.207 m
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S
169.951 703.261 m
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S
165.808 688.636 m
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172.698 684.996 m
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S
173.9 685.207 m
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S
q
136.249 652.041 73.986 74.1 re
W n
0 842.013 595.008 -842.004 re
W n
0 G
0.097 w
140.717 656.656 m
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140.717 725.361 m
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209.423 725.361 m
209.423 656.656 l
140.717 725.361 m
140.717 656.656 l
140.717 656.656 m
209.423 656.656 l
140.717 725.361 m
140.717 656.656 l
149.59 656.656 m
149.59 657.355 l
149.59 725.361 m
149.59 724.678 l
S
BT
/F10 1 Tf
3.51 0 0 3.51 148.615 652.837 Tm
0 Tc
(5)Tj
ET
160.656 656.656 m
160.656 657.355 l
160.656 725.361 m
160.656 724.678 l
S
BT
3.51 0 0 3.51 158.7063 652.837 Tm
(10)Tj
ET
171.739 656.656 m
171.739 657.355 l
171.739 725.361 m
171.739 724.678 l
S
BT
3.51 0 0 3.51 169.7888 652.837 Tm
(15)Tj
ET
182.821 656.656 m
182.821 657.355 l
182.821 725.361 m
182.821 724.678 l
S
BT
3.51 0 0 3.51 180.8712 652.837 Tm
(20)Tj
ET
193.904 656.656 m
193.904 657.355 l
193.904 725.361 m
193.904 724.678 l
S
BT
3.51 0 0 3.51 191.9538 652.837 Tm
(25)Tj
ET
204.986 656.656 m
204.986 657.355 l
204.986 725.361 m
204.986 724.678 l
S
BT
3.51 0 0 3.51 203.0363 652.837 Tm
(30)Tj
ET
140.717 716.505 m
141.4 716.505 l
209.423 716.505 m
208.74 716.505 l
S
BT
3.51 0 0 3.51 138.1987 715.2045 Tm
(5)Tj
ET
140.717 705.422 m
141.4 705.422 l
209.423 705.422 m
208.74 705.422 l
S
BT
3.51 0 0 3.51 136.2487 704.1221 Tm
(10)Tj
ET
140.717 694.34 m
141.4 694.34 l
209.423 694.34 m
208.74 694.34 l
S
BT
3.51 0 0 3.51 136.2487 693.0396 Tm
(15)Tj
ET
140.717 683.257 m
141.4 683.257 l
209.423 683.257 m
208.74 683.257 l
S
BT
3.51 0 0 3.51 136.2487 681.957 Tm
(20)Tj
ET
140.717 672.175 m
141.4 672.175 l
209.423 672.175 m
208.74 672.175 l
S
BT
3.51 0 0 3.51 136.2487 670.8745 Tm
(25)Tj
ET
140.717 661.092 m
141.4 661.092 l
209.423 661.092 m
208.74 661.092 l
S
BT
3.51 0 0 3.51 136.2487 659.7921 Tm
(30)Tj
ET
140.717 656.656 m
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140.717 725.361 m
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209.423 725.361 m
209.423 656.656 l
140.717 725.361 m
140.717 656.656 l
S
EMC
/EmbeddedDocument /MC2 BDC
Q
q
212.88 652.038 94.344 74.164 re
W n
0 842.013 595.008 -842.004 re
W n
1 g
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f
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f*
1 G
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221.076 656.558 l
S
0 G
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245.856 656.558 m
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259.622 656.558 m
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287.155 656.558 m
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300.922 656.558 m
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S
0.095 w []0 d
221.076 723.847 m
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221.076 656.558 m
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306.428 656.558 m
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221.076 656.558 m
221.076 723.847 l
221.076 656.558 m
306.428 656.558 l
221.076 656.558 m
221.076 723.847 l
232.089 656.558 m
232.089 657.418 l
232.089 723.847 m
232.089 723.003 l
S
BT
/F10 1 Tf
3.4376 0 0 3.4376 231.1345 652.8183 Tm
0 g
0 Tc
(5)Tj
ET
245.856 656.558 m
245.856 657.418 l
245.856 723.847 m
245.856 723.003 l
S
BT
3.4376 0 0 3.4376 243.946 652.8183 Tm
(10)Tj
ET
259.622 656.558 m
259.622 657.418 l
259.622 723.847 m
259.622 723.003 l
S
BT
3.4376 0 0 3.4376 257.7124 652.8183 Tm
(15)Tj
ET
273.389 656.558 m
273.389 657.418 l
273.389 723.847 m
273.389 723.003 l
S
BT
3.4376 0 0 3.4376 271.4789 652.8183 Tm
(20)Tj
ET
287.155 656.558 m
287.155 657.418 l
287.155 723.847 m
287.155 723.003 l
S
BT
3.4376 0 0 3.4376 285.2453 652.8183 Tm
(25)Tj
ET
300.922 656.558 m
300.922 657.418 l
300.922 723.847 m
300.922 723.003 l
S
BT
3.4376 0 0 3.4376 299.0117 652.8183 Tm
(30)Tj
ET
221.076 656.558 m
221.92 656.558 l
306.428 656.558 m
305.569 656.558 l
S
BT
3.4376 0 0 3.4376 218.6094 655.2851 Tm
(0)Tj
ET
221.076 667.731 m
221.92 667.731 l
306.428 667.731 m
305.569 667.731 l
S
BT
3.4376 0 0 3.4376 214.7898 666.4574 Tm
(200)Tj
ET
221.076 678.887 m
221.92 678.887 l
306.428 678.887 m
305.569 678.887 l
S
BT
3.4376 0 0 3.4376 214.7898 677.6138 Tm
(400)Tj
ET
221.076 690.043 m
221.92 690.043 l
306.428 690.043 m
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S
BT
3.4376 0 0 3.4376 214.7898 688.7701 Tm
(600)Tj
ET
221.076 701.2 m
221.92 701.2 l
306.428 701.2 m
305.569 701.2 l
S
BT
3.4376 0 0 3.4376 214.7898 699.9265 Tm
(800)Tj
ET
221.076 712.356 m
221.92 712.356 l
306.428 712.356 m
305.569 712.356 l
S
BT
3.4376 0 0 3.4376 212.88 711.0829 Tm
(1000)Tj
ET
221.076 723.512 m
221.92 723.512 l
306.428 723.512 m
305.569 723.512 l
S
BT
3.4376 0 0 3.4376 212.88 722.2393 Tm
(1200)Tj
ET
221.076 723.847 m
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221.076 656.558 m
306.428 656.558 l
306.428 656.558 m
306.428 723.847 l
221.076 656.558 m
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S
Q
q
221.076 656.542 85.368 67.304 re
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0 842.013 595.008 -842.004 re
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S
EMC
/EmbeddedDocument /MC3 BDC
Q
q
310.129 652.041 73.986 74.1 re
W n
0 842.013 595.008 -842.004 re
W n
1 g
310.122 726.147 73.998 -74.124 re
f
314.598 725.361 68.705 -68.705 re
f
1 G
0.097 w
314.598 725.361 m
314.598 656.656 l
383.303 656.656 l
383.303 725.361 l
314.598 725.361 l
S
Q
q
314.598 656.64 68.721 68.721 re
W n
q
70.915 0 0 70.915 313.5088 655.5508 cm
/Im2 Do
Q
Q
q
310.129 652.041 73.986 74.1 re
W n
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W n
0 0 1 RG
1.365 w
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S
1 1 0 RG
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S
0 0 1 RG
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340.24 699.913 m
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S
1 1 0 RG
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S
Q
0 0 1 RG
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328.995 691.642 m
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S
352.005 690.846 m
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S
353.289 706.966 m
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S
1 1 0 RG
0.585 w
342.076 711.825 m
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S
328.995 691.642 m
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[(of)-376.5(t)7.9(h)6(e)-394.2(t)7.9(arget)-365.4(s)1.5(t)7.9(r)-1.3(u)6(c)3.3(t)8(u)6(re.)-380.2(T)88.3(o)-386.8(i)5.2(n)6(c)3.3(rease)]TJ
-19.1275 -1.2045 TD
-0.001 Tc
[(the)-327.4(r)-6.8(o)-6.9(bustness)-317.2(o)-6.9(f)-321.8(t)2.4(his)-329.3(a)-6.9(ppr)-6.8(o)-6.9(a)-6.9(c)21.9(h,)-301.4(w)22.6(e)-315.4(r)-6.8(u)0.5(n)]TJ
/F8 1 Tf
17.5496 0 TD
0 Tc
(N)Tj
/F3 1 Tf
6.9738 0 0 6.9738 317.64 647.0071 Tm
(1)Tj
/F2 1 Tf
9.9626 0 0 9.9626 325.32 648.447 Tm
-0.0004 Tc
[(mea)-6.3(n)-312.1(shift)-334.2(p)1.1(r)-6.2(o)-30.4(cedur)-6.2(es)-304.6(initia)-6.3(lized)-324.1(b)25.2(y)]TJ
-19.1275 -1.2045 TD
-0.0005 Tc
[(sa)-6.4(mpling)-247.3(t)3(he)-242.6(neig)-6.4(h)25.1(b)-23.1(o)-6.4(r)-6.3(ho)-30.5(o)-30.5(d)-239.9(o)-6.4(f)]TJ
/F9 1 Tf
13.0207 0 TD
0 Tc
(x)Tj
/F13 1 Tf
6.9738 0 0 6.9738 270.48 635.007 Tm
(p)Tj
/F2 1 Tf
9.9626 0 0 9.9626 277.56 636.447 Tm
-0.0017 Tc
[(unifo)-7.6(r)-7.5(m)0.5(ly)80.4(.)-241.9(T)-2.2(he)-255.9(ma)-67.8(jo)-7.6(r)-7.5(i)-1(t)25.8(y)-232.8(o)-7.6(f)-238.2(the)-255.9(p)-0.2(r)-7.5(o)-31.7(cedur)-7.5(es)-233.6(c)-2.9(o)-7.6(n)-0.2(-)]TJ
-14.3336 -1.1925 TD
0.0044 Tc
[(v)26.3(e)3.2(rgen)5.9(ce)-273.9(at)-281.2(t)7.8(h)5.9(e)-297.9(s)1.4(am)6.6(e)-285.9(l)5.1(o)-25.6(c)3.2(at)7.8(i)5.1(o)-1.5(n)-283.2(i)5.1(n)5.9(d)5.9(i)5.1(cat)7.8(e)3.2(s)-287.7(t)7.8(h)5.9(e)-297.9(l)5.1(o)-25.6(cat)7.8(i)5.1(on)-283.2(of)-292.3(t)7.9(h)5.9(e)-297.9(m)6.6(axi)5.1(m)30.7(u)5.9(m)6.6(.)-283.9(T)3.9(h)5.9(e)-297.9(p)-18.2(o)-1.5(i)5.1(n)30(t)]TJ
0 -1.2045 TD
[(p)5.9(r)-1.4(o)22.6(x)2.2(i)5.1(m)6.6(i)5.1(t)31.9(y)-335.1(i)5.1(s)-335.9(d)5.9(e)5.9(n)5.9(e)3.2(d)-355.5(b)30(y)-335.1(u)5.9(si)5.1(n)5.9(g)-350.8(t)7.9(h)5.9(e)-346.1(M)5.6(ah)5.9(al)5.1(an)5.9(ob)5.9(i)5.1(s)-323.9(d)5.9(i)5.1(st)7.9(an)5.9(ce)-346.1(w)3.9(i)5.1(t)7.8(h)]TJ
/F9 1 Tf
26.9086 0 TD
0 Tc
(H)Tj
/F2 1 Tf
0.9034 0 TD
-0.0013 Tc
[(.)-349.9(T)-1.8(his)-353.6(a)-7.2(ppr)-7.1(o)-7.2(a)-7.2(c)21.6(h)]TJ
-27.812 -1.1925 TD
0.0014 Tc
[(is)-338.9(ecien)27(t)-332.4(b)-21.2(ecause)-325(i)2.1(t)-344.5(d)2.9(o)-28.6(e)0.2(s)-326.9(n)2.9(ot)-332.4(require)-325(t)4.8(he)]TJ
18.5494 0 TD
-0.0006 Tc
[(time-)-4.5(c)-1.8(o)-6.5(n)0.9(suming)-343.8(explicit)-334.4(co)-6.5(nstr)-6.4(uctio)-6.5(n)]TJ
-18.5494 -1.2045 TD
0.0059 Tc
(of)Tj
/F8 1 Tf
1.1443 0 TD
0 Tc
(F)Tj
/F2 1 Tf
0.7829 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F2 1 Tf
0.6023 0 TD
(;)Tj
/F9 1 Tf
0.4457 0 TD
(H)Tj
/F2 1 Tf
0.9034 0 TD
0.3338 Tc
[(\)f)338.2(r)328(o)327.9(m)]TJ
/F8 1 Tf
3.0835 0 TD
0 Tc
(f)Tj
/F2 1 Tf
0.6023 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F2 1 Tf
0.6023 0 TD
-0.0034 Tc
(\).)Tj
/F9 1 Tf
-8.9374 -2.9872 TD
0 Tc
[(2.)-5.8(5)-1147.4(R)-4.7(obust)-408(A)2.2(ni)-5.8(sotropi)-5.8(c)-416.4(Co)33(v)64.9(a)5(ri)-5.8(an)]TJ
17.3689 0 TD
-0.0007 Tc
[(ce)-449.3(Es)-4.8(ti)-6.5(m)-6(a)4.3(ti)-6.5(on)-409.7(b)35.9(y)-441.7(Cons)-4.8(trai)-6.5(ned)]TJ
-14.7431 -1.2045 TD
-0.0012 Tc
[(Least-Squares)-390.7(i)-7(n)-386.1(t)0.4(he)-377.5(Basi)-7(n)-386.1(o)-4.4(f)-372.5(A)37.1(ttracti)-7(o)-4.4(n)]TJ
/F2 1 Tf
-2.6258 -1.9874 TD
-0.0008 Tc
[(In)-276.4(the)-279.1(s)-3.8(equel)-277.1(w)22.8(e)-267(e)-2(stima)-6.7(t)2.6(e)-279.1(t)2.6(he)-279.1(fully)]TJ
15.0322 0 TD
0.0015 Tc
[(parameterized)-250(co)19.7(v)59.5(a)-4.4(riance)-252.7(matrix)]TJ
/F9 1 Tf
14.4179 0 TD
0 Tc
()Tj
/F2 1 Tf
1.1081 0 TD
-0.0014 Tc
[(in)-276.9(E)-7.4(q)-3.6(.\(1)-7.3(\))2.1(,)]TJ
-30.5583 -1.2045 TD
0.0041 Tc
[(c)27(h)5.6(aract)7.5(e)2.9(ri)4.8(zi)4.8(n)5.6(g)-363.1(t)7.6(h)5.6(e)]TJ
/F8 1 Tf
8.2629 0 TD
0 Tc
(d)Tj
/F2 1 Tf
0.5179 0 TD
0.0048 Tc
[(-d)6.3(i)5.5(m)7(en)6.3(si)5.5(on)6.3(al)-367.9(an)6.3(i)5.5(s)1.8(ot)8.3(rop)6.3(i)5.5(c)-369.8(s)1.8(p)6.3(r)-1(ead)-379.2(a)-1.1(n)6.3(d)-379.2(ori)5.5(e)3.6(n)30.4(t)8.2(at)8.2(i)5.5(o)-1.1(n)-367.1(o)-1.1(f)-376.2(t)8.2(h)6.3(e)-393.9(si)5.5(g-)]TJ
-8.7808 -1.1925 TD
-0.0015 Tc
[(na)-7.4(l)]TJ
/F8 1 Tf
1.6743 0 TD
0 Tc
(f)Tj
/F2 1 Tf
0.9275 0 TD
0.0048 Tc
[(arou)6.3(n)6.3(d)-318.9(t)8.2(h)6.3(e)-333.7(l)5.5(o)-25.2(c)3.6(al)-319.7(m)7(a)-1.1(xi)5.5(m)31.1(u)6.3(m)]TJ
/F9 1 Tf
12.1534 0 TD
0 Tc
(u)Tj
/F2 1 Tf
0.6384 0 TD
0.0001 Tc
[(.)-336.4(C)-0.4(la)-5.8(ssica)-5.8(l)-312.3(s)-2.9(ca)-5.8(le-)-3.8(s)-2.9(pa)-5.8(ce)-314.3(a)-5.8(ppr)-5.7(o)-5.8(a)-5.8(c)23(hes)-304.1(r)-5.7(elying)-331(o)-5.8(n)]TJ
-15.3936 -1.2045 TD
-0.0025 Tc
(the)Tj
/F8 1 Tf
1.8068 0 TD
0 Tc
()Tj
/F2 1 Tf
0.5782 0 TD
0.004 Tc
[(-n)5.5(orm)6.2(a)-1.9(l)4.7(i)4.7(zed)-380(Lap)5.5(l)4.7(aci)4.7(a)-1.9(n)-392([)4.7(12])-404.8(are)-394.7(l)4.7(i)4.7(m)6.2(i)4.7(t)7.5(ed)-416.1(t)7.4(o)-411.4(t)7.4(h)5.5(e)-418.8(i)4.7(sot)7.4(r)-1.8(op)5.5(i)4.7(c)-394.7(case)-394.7(t)7.4(h)29.6(u)5.5(s)-408.6(n)5.5(o)-1.9(t)-414.1(a)-1.9(p)5.5(-)]TJ
-2.3849 -1.1925 TD
-0.001 Tc
[(plica)-6.9(b)0.5(le)-399.7(to)-404.4(this)-413.6(pr)-6.8(o)-6.9(b)0.5(lem.)-385.7(Ano)-6.9(t)2.4(her)-404.3(a)-6.9(ppr)-6.8(o)-6.9(a)-6.9(c)21.9(h)-385(i)-0.3(s)-401.5(t)2.4(he)-399.7(sta)-6.9(nda)-6.9(r)-6.8(d)-385(sa)-6.9(mple)-399.7(estima)-6.9(tio)-6.9(n)]TJ
0 -1.2045 TD
0.0059 Tc
(of)Tj
/F9 1 Tf
1.2527 0 TD
0 Tc
()Tj
/F2 1 Tf
1.2888 0 TD
-0.0014 Tc
[(b)24.2(y)-449.3(tr)-7.2(ea)-7.3(ting)]TJ
/F8 1 Tf
5.4082 0 TD
0 Tc
(f)Tj
/F2 1 Tf
1.0479 0 TD
0.0046 Tc
[(as)-432.1(a)-447(d)6.1(en)6.1(si)5.3(t)32.1(y)-455.3(f)9(u)6.1(n)6.1(c)3.4(t)8(i)5.3(on)-451.6([)5.3(13,)-428.3(p)6.1(.)5.3(179])5.3(.)-440.3(H)7.8(o)22.8(w)28.2(ev)26.5(er,)-416.2(t)8.1(h)6.1(i)5.3(s)-456.2(a)-1.3(p)6.1(p)6.1(r)-1.2(oac)27.5(h)]TJ
-8.9976 -1.2045 TD
-0.0007 Tc
[(b)-23.3(eco)-6.6(mes)-341(s)-3.7(ub)-23.3(o)-6.6(p)0.8(tima)-6.6(l)-337.2(i)0(n)-336.5(t)2.7(he)-351.2(pr)-6.5(esence)-327.1(o)-6.6(f)-333.5(the)-339.2(m)1.5(a)-6.6(r)-6.5(g)-6.6(i)0(n-)-4.6(tr)-6.5(unca)-6.6(t)2.7(io)-6.6(ns.)-313.1(A)2.5(ddr)-6.5(essing)-343.9(this)]TJ
0 -1.1925 TD
0.002 Tc
[(issue,)-274.3(w)25.6(e)-276.3(presen)27.6(t)-271.6(a)-268.9(constrai)]TJ
11.7198 0 TD
0.0039 Tc
[(n)5.4(e)2.7(d)-271.7(l)4.6(east)7.3(-squ)5.4(ares)-252.1(f)8.3(r)-1.9(am)6.1(ew)27.5(ork)-251.2(f)8.3(or)-279(t)7.3(h)5.4(e)-274.4(e)2.7(st)7.3(i)4.6(m)6.1(at)7.4(i)4.6(o)-2(n)-271.7(o)-2(f)-280.7(t)7.3(h)5.4(e)]TJ
-11.7198 -1.2045 TD
0.004 Tc
[(an)5.5(i)4.7(s)1(ot)7.4(rop)5.5(i)4.7(c)-394.7(f)8.4(u)5.5(l)4.7(l)4.7(y)1.8(-p)5.5(aram)6.2(et)7.4(eri)4.7(zed)-392(co)22.2(v)62(a)-1.9(ri)4.7(an)5.5(ce)-394.7(of)-401.1(i)4.7(n)29.6(t)7.4(e)2.8(rest)-414.1(b)5.5(a)-1.9(sed)-404(o)-1.9(n)-404(t)7.4(h)5.5(e)-418.8(m)6.2(e)2.8(an)-404(sh)5.5(i)4.7(f)8.4(t)]TJ
T*
0.0038 Tc
[(v)25.7(ect)7.2(ors)-312.4(c)2.6(ol)4.5(l)4.5(ect)7.2(ed)-319.9(i)4.5(n)-332(t)7.2(h)5.3(e)-334.7(b)5.3(asi)4.5(n)-319.9(of)-329(at)7.2(t)7.2(r)-2(act)7.2(i)4.5(on)-319.9(of)]TJ
/F9 1 Tf
19.9586 0 TD
0 Tc
(u)Tj
/F2 1 Tf
0.6384 0 TD
(.)Tj
-19.0914 -1.1925 TD
0.0044 Tc
[(W)8.3(i)5.1(t)7.8(h)-391.6(t)7.8(h)5.9(e)-406.3(s)1.4(i)5.1(g)-1.5(n)5.9(a)-1.5(l)-368.3(m)6.6(o)-25.6(d)5.9(el)-404.4(of)-376.6(Eq.)5.1(\()7.9(1\))7.9(,)-392.3(t)7.8(h)5.9(e)-394.3(d)5.9(e)3.2()5.9(n)5.9(i)5.1(t)7.8(i)5.1(on)-391.6(of)-388.7(t)7.9(h)5.9(e)-394.3(m)6.6(ean)-391.6(s)1.4(h)5.9(i)5.1(f)8.8(t)-389.6(v)26.3(ect)7.8(or)-386.9(of)]TJ
-1.5056 -1.2045 TD
0.0046 Tc
[(Eq.)5.3(\()8(5\))-317.2(can)-319.1(b)-18(e)-333.9(r)-1.2(ew)4.1(ri)5.3(t)8(t)8(e)3.4(n)-331.2(a)-1.3(s)-323.7(a)-326.5(f)9(u)6.1(n)6.1(c)3.4(t)8(i)5.3(on)-331.2(of)]TJ
/F9 1 Tf
17.7423 0 TD
0 Tc
()Tj
/F2 1 Tf
0.8311 0 TD
(,)Tj
/F9 1 Tf
-12.563 -3.8062 TD
(m)Tj
/F2 1 Tf
0.9516 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(y)Tj
/F13 1 Tf
6.9738 0 0 6.9738 214.2 355.287 Tm
(j)Tj
/F2 1 Tf
9.9626 0 0 9.9626 218.4 357.687 Tm
(;)Tj
/F9 1 Tf
0.4457 0 TD
(H)Tj
/F2 1 Tf
0.9034 0 TD
0.2736 Tc
(\)=)Tj
/F9 1 Tf
1.7224 0 TD
0 Tc
(H)Tj
/F11 1 Tf
1.0238 0.7709 TD
()Tj
/F8 1 Tf
0.8311 0 TD
(F)Tj
/F2 1 Tf
0.7829 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(y)Tj
/F13 1 Tf
6.9738 0 0 6.9738 285.36 362.967 Tm
(j)Tj
/F2 1 Tf
9.9626 0 0 9.9626 289.56 365.367 Tm
(;)Tj
/F9 1 Tf
0.4457 0 TD
(H)Tj
/F2 1 Tf
0.8913 0 TD
(\))Tj
ET
q
47.64 0 0 -0.48 259.188 360.4351 cm
/Im3 Do
Q
BT
/F8 1 Tf
9.9626 0 0 9.9626 263.28 350.847 Tm
(F)Tj
/F2 1 Tf
0.7829 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(y)Tj
/F13 1 Tf
6.9738 0 0 6.9738 281.16 348.447 Tm
(j)Tj
/F2 1 Tf
9.9626 0 0 9.9626 285.36 350.847 Tm
(;)Tj
/F9 1 Tf
0.4457 0 TD
(H)Tj
/F2 1 Tf
0.9034 0 TD
(\))Tj
/F11 1 Tf
-6.0586 -2.3608 TD
()Tj
/F9 1 Tf
1.06 0 TD
(H)Tj
/F8 1 Tf
1.0238 0.7709 TD
-0.0013 Tc
()Tj
/F2 1 Tf
1.3009 0 TD
0 Tc
(\()Tj
/F9 1 Tf
0.3854 0 TD
(y)Tj
/F13 1 Tf
6.9738 0 0 6.9738 282.36 332.487 Tm
(j)Tj
/F2 1 Tf
9.9626 0 0 9.9626 286.56 335.007 Tm
(;)Tj
/F9 1 Tf
0.4457 0 TD
(u)Tj
/F8 1 Tf
0.6263 0 TD
(,)Tj
/F9 1 Tf
0.4457 0 TD
()Tj
/F2 1 Tf
1.06 0 TD
(+)Tj
/F9 1 Tf
0.9997 0 TD
(H)Tj
/F2 1 Tf
0.9034 0 TD
-0.0034 Tc
(\)\()Tj
/F9 1 Tf
0.7709 0 TD
0 Tc
()Tj
/F2 1 Tf
1.0479 0 TD
(+)Tj
/F9 1 Tf
1.0118 0 TD
(H)Tj
/F2 1 Tf
0.8913 0 TD
(\))Tj
/F12 1 Tf
6.9738 0 0 6.9738 372.12 338.607 Tm
()Tj
/F3 1 Tf
0.8948 0 TD
(1)Tj
/F2 1 Tf
9.9626 0 0 9.9626 382.92 335.007 Tm
(\()Tj
/F9 1 Tf
0.3854 0 TD
(u)Tj
/F11 1 Tf
0.8552 0 TD
()Tj
/F9 1 Tf
0.9997 0 TD
(y)Tj
/F13 1 Tf
6.9738 0 0 6.9738 411.48 332.487 Tm
(j)Tj
/F2 1 Tf
9.9626 0 0 9.9626 415.68 335.007 Tm
(\))Tj
ET
q
160.44 0 0 -0.48 259.188 330.075 cm
/Im3 Do
Q
BT
/F8 1 Tf
9.9626 0 0 9.9626 301.44 320.487 Tm
-0.0013 Tc
()Tj
/F2 1 Tf
1.3009 0 TD
0 Tc
(\()Tj
/F9 1 Tf
0.3854 0 TD
(y)Tj
/F13 1 Tf
6.9738 0 0 6.9738 324.6 318.087 Tm
(j)Tj
/F2 1 Tf
9.9626 0 0 9.9626 328.8 320.487 Tm
(;)Tj
/F9 1 Tf
0.4457 0 TD
(u)Tj
/F8 1 Tf
0.6384 0 TD
(,)Tj
/F9 1 Tf
0.4457 0 TD
()Tj
/F2 1 Tf
1.0479 0 TD
(+)Tj
/F9 1 Tf
0.9997 0 TD
(H)Tj
/F2 1 Tf
0.9034 0 TD
(\))Tj
-13.5506 -1.6502 TD
(=)Tj
/F9 1 Tf
1.06 0 TD
(H)Tj
/F2 1 Tf
0.9034 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
()Tj
/F2 1 Tf
1.06 0 TD
(+)Tj
/F9 1 Tf
0.9997 0 TD
(H)Tj
/F2 1 Tf
0.8913 0 TD
(\))Tj
/F12 1 Tf
6.9738 0 0 6.9738 295.08 308.247 Tm
()Tj
/F3 1 Tf
0.8948 0 TD
(1)Tj
/F2 1 Tf
9.9626 0 0 9.9626 305.88 304.047 Tm
(\()Tj
/F9 1 Tf
0.3854 0 TD
(u)Tj
/F11 1 Tf
0.8552 0 TD
()Tj
/F9 1 Tf
0.9997 0 TD
(y)Tj
/F13 1 Tf
6.9738 0 0 6.9738 334.44 301.647 Tm
(j)Tj
/F2 1 Tf
9.9626 0 0 9.9626 338.64 304.047 Tm
(\))Tj
/F8 1 Tf
0.3854 0 TD
(.)Tj
/F2 1 Tf
12.587 0 TD
-0.0034 Tc
[(\(7)-9.3(\))]TJ
-33.4369 -2.1801 TD
-0.0005 Tc
[(F)86.2(u)1(r)-6.3(t)2.9(her)-331.5(r)-6.3(ewr)-6.3(i)0.2(ting)-331.6(E)-6.5(q)-2.7(.\(7)-6.4(\))-322.3(r)-6.3(e)-1.7(sults)-328.8(i)0.2(n)-336.3(a)-331.6(linea)-6.4(r)-331.5(m)1.7(a)-6.4(t)2.9(r)-6.3(i)0.2(x)-327.9(e)-1.7(qua)-6.4(t)2.9(io)-6.4(n)-324.2(o)-6.4(f)-333.3(unkno)17.7(wn)]TJ
/F9 1 Tf
31.7266 0 TD
0 Tc
()Tj
/F2 1 Tf
0.8311 0 TD
(,)Tj
/F9 1 Tf
-18.7662 -3.3846 TD
0.0006 Tc
(H)Tj
/F12 1 Tf
6.9738 0 0 6.9738 289.32 252.927 Tm
0 Tc
()Tj
/F3 1 Tf
0.8948 0 TD
(1)Tj
/F9 1 Tf
9.9626 0 0 9.9626 300.12 248.607 Tm
(m)Tj
/F13 1 Tf
6.9738 0 0 6.9738 309.6 247.167 Tm
(j)Tj
/F2 1 Tf
9.9626 0 0 9.9626 316.56 248.607 Tm
(=)Tj
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[(In)-408.2(this)-424.8(sectio)-6.1(n,)-409(w)23.4(e)-411(pr)-6(esen)25.4(t)-406.3(a)-403.6(g)-6.1(o)-30.2(o)-30.2(dness-o)-6.1(f)4.2(-t)-394.2(m)2(ea)-6.1(sur)-6(e)-398.9(fo)-6.1(r)-415.5(v)57.8(a)-6.1(lida)-6.1(t)3.2(ing)-415.6(t)3.2(he)-423(r)-6(e)-1.4(sult-)]TJ
0 -1.1925 TD
-0.0008 Tc
[(ing)-380.1(e)-2(stima)-6.7(t)2.6(es.)-373.5(Suc)22.1(h)-384.8(s)-3.8(ta)-6.7(tistica)-6.7(l)-361.4(v)57.2(a)-6.7(lida)-6.7(t)2.6(io)-6.7(n)-372.7(g)-6.7(iv)21.1(es)-365.2(a)-380.1(p)0.7(r)-6.6(i)-0.1(ncipled)-384.8(m)1.4(ea)-6.7(ns)-377.2(fo)-6.7(r)-368(r)-6.6(ejecting)]TJ
0 -1.2045 TD
-0.0001 Tc
[(a)-6(cciden)25.5(t)3.3(a)-6(l)-384.8(ill-estima)-6(tes.)-396.8(W)88.2(e)-398.8(tr)-5.9(ea)-6(t)-382.1(t)3.4(his)-412.7(p)1.4(r)-5.9(o)-6(blem)-383.3(a)-6(s)-388.6(a)-6(n)1.4(a)-6(l)0.6(ysis)-388.6(o)-6(f)-393.2(c)22.8(h)1.4(i-squa)-6(r)-5.9(e)-374.7(tting)]TJ
0 -1.1925 TD
-0.0011 Tc
[(r)-6.9(e)-2.3(sidua)-7(l)-277.4(e)-2.3(r)-6.9(r)-6.9(o)-7(r)-6.9(s)-4.1(.)-265.3(W)87.2(e)-303.4(e)-2.3(mplo)17.1(y)-292.4(a)-296.1(linea)-7(r)-284(m)1.1(o)-31.1(d)0.4(el)-289.4(with)-300.7(a)-7(n)-288.7(a)-7(dditiv)20.8(e)-291.4(pa)-7(r)-6.9(a)-7(meter)-284(o)-7(f)-285.7(t)2.4(he)-303.5(DC)]TJ
0 -1.2045 TD
0.0003 Tc
[(comp)-22.3(onen)25.9(t;)]TJ
/F8 1 Tf
5.4925 0 TD
0 Tc
(f)Tj
/F11 1 Tf
1.0359 0 TD
()Tj
/F8 1 Tf
1.2165 0 TD
()Tj
/F11 1 Tf
0.9275 0 TD
()Tj
/F8 1 Tf
1.072 0 TD
()Tj
/F2 1 Tf
0.9516 0 TD
(+)Tj
/F8 1 Tf
1.06 0 TD
()Tj
/F2 1 Tf
0.6143 0 TD
-0.0006 Tc
[(.)-433.5(R)0.8(eca)-6.5(ll)-433.5(tha)-6.5(t)-430.8(o)-6.5(u)0.9(r)-428(e)-1.8(stima)-6.5(t)2.9(io)-6.5(n)-420.7(m)1.6(o)-30.6(d)0.9(el)-433.5(is)-425.2(witho)-6.5(u)0.9(t)-442.8(t)2.8(he)]TJ
-12.3703 -1.2045 TD
0.0042 Tc
[(D)9.3(C)3.7(.)-296.2(T)3.7(h)5.7(e)-286.1(ad)5.7(d)5.7(i)4.9(t)7.6(i)4.9(on)5.7(al)-284.1(d)5.7(e)3(gree)-274.1(of)-280.5(f)8.6(r)-1.6(eed)5.7(om)-282.7(i)4.9(n)29.8(t)7.7(r)-1.6(o)-25.8(d)5.7(u)5.7(ced)-283.4(serv)26.1(es)-275.9(as)-287.9(an)5.7(ot)7.6(h)5.7(e)3(r)-278.7(g)-1.7(o)-25.8(o)-25.8(d)5.7(n)5.7(e)3(ss-of)8.6(-)]TJ
0 -1.1925 TD
-0.0013 Tc
[(t)-407.4(indica)-7.2(to)-7.2(r)-7.1(.)-386(Giv)20.6(e)-2.5(n)-397.3(t)2.1(he)-412.1(estima)-7.2(te)-400(pa)-7.2(ir)-392.6(\()]TJ
/F9 1 Tf
17.2485 0 TD
0 Tc
(u)Tj
/F12 1 Tf
6.9738 0 0 6.9738 313.08 624.567 Tm
()Tj
/F2 1 Tf
9.9626 0 0 9.9626 317.64 620.967 Tm
(,)Tj
/F9 1 Tf
0.277 0 TD
()Tj
/F12 1 Tf
6.9738 0 0 6.9738 328.68 625.287 Tm
()Tj
/F2 1 Tf
9.9626 0 0 9.9626 333.24 620.967 Tm
-0.001 Tc
[(\),)-409.8(the)-399.7(f)3.4(o)-6.9(llo)17.2(wing)-392.3(denes)-401.5(t)2.5(he)-411.8(sig)-6.9(n)0.5(a)-6.9(l)]TJ
-19.9224 -1.3129 TD
0.0028 Tc
[(resp)-19.8(onse)-323.6(est)6.2(i)3.5(m)5(a)-3.1(t)6.2(e)]TJ
8.2629 0.265 TD
0 Tc
()Tj
/F8 1 Tf
-0.2168 -0.265 TD
(f)Tj
/F2 1 Tf
0.9275 0 TD
-0.0004 Tc
[(with)-336.2(t)27.1(w)23.2(o)-331.5(unkno)17.8(wns,)]TJ
-1.5056 -1.879 TD
0 Tc
()Tj
/F8 1 Tf
-0.2168 -0.265 TD
(f)Tj
/F2 1 Tf
0.6023 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F8 1 Tf
0.6023 0 TD
(,)Tj
/F9 1 Tf
0.4457 0 TD
(u)Tj
/F12 1 Tf
6.9738 0 0 6.9738 233.64 590.7271 Tm
()Tj
/F8 1 Tf
9.9626 0 0 9.9626 238.2 586.527 Tm
(,)Tj
/F9 1 Tf
0.4457 0 TD
()Tj
/F12 1 Tf
6.9738 0 0 6.9738 250.92 590.967 Tm
()Tj
/F2 1 Tf
9.9626 0 0 9.9626 255.48 586.527 Tm
(;)Tj
/F8 1 Tf
0.4457 0 TD
-0.0013 Tc
[(,)-169.2()]TJ
/F2 1 Tf
1.6983 0 TD
0.2856 Tc
(\)=)Tj
/F8 1 Tf
1.7345 0 TD
0 Tc
()Tj
/F11 1 Tf
0.8672 0 TD
()Tj
/F8 1 Tf
0.9997 0 TD
()Tj
/F2 1 Tf
0.6625 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F2 1 Tf
0.6143 0 TD
(;)Tj
/F9 1 Tf
0.4457 0 TD
(u)Tj
/F12 1 Tf
6.9738 0 0 6.9738 340.08 590.7271 Tm
()Tj
/F8 1 Tf
9.9626 0 0 9.9626 344.64 586.527 Tm
(,)Tj
/F9 1 Tf
0.4457 0 TD
()Tj
/F12 1 Tf
6.9738 0 0 6.9738 357.36 590.967 Tm
()Tj
/F2 1 Tf
9.9626 0 0 9.9626 361.92 586.527 Tm
0.2254 Tc
(\)+)Tj
/F8 1 Tf
1.614 0 TD
0 Tc
()Tj
/F11 1 Tf
0.6143 0 TD
(|)Tj
/F9 1 Tf
0.277 -0.3373 TD
(x)Tj
/F12 1 Tf
6.9738 0 0 6.9738 393 583.1671 Tm
()Tj
/F11 1 Tf
9.9626 0 0 9.9626 398.4 583.1671 Tm
(S)Tj
/F8 1 Tf
0.7227 0.3373 TD
(.)Tj
/F2 1 Tf
5.7455 0 TD
0.0059 Tc
[(\()9.3(12\))]TJ
-32.931 -2.3849 TD
-0.0009 Tc
[(The)-315.3(c)22(hi-)-4.8(s)-3.9(qua)-6.8(r)-6.7(e)-279.2(s)-3.9(ta)-6.8(tistic)-315.3(indica)-6.8(tes)-305.1(t)2.6(he)-315.3(r)-6.7(e)-2.1(sidua)-6.8(l)-289.2(e)-2.1(r)-6.7(r)-6.7(o)-6.8(r)-295.8(o)-6.8(f)-297.6(t)2.5(he)-315.3(tted)-312.6(m)1.3(o)-30.9(d)0.6(el)]TJ
31.0881 0.265 TD
0 Tc
()Tj
/F8 1 Tf
-0.2168 -0.265 TD
(f)Tj
/F2 1 Tf
0.5902 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F2 1 Tf
0.6143 0 TD
0.0059 Tc
[(\))-303.8([)6.6(16,)]TJ
-32.4613 -1.2045 TD
[(p)7.4(.)6.6(660])6.6(,)]TJ
/F8 1 Tf
5.4443 -2.9149 TD
0 Tc
()Tj
/F3 1 Tf
6.9738 0 0 6.9738 195.24 525.807 Tm
(2)Tj
/F11 1 Tf
9.9626 0 0 9.9626 202.44 521.7271 Tm
()Tj
/F15 1 Tf
1.06 0.9516 TD
()Tj
/F13 1 Tf
6.9738 0 0 6.9738 213.48 509.727 Tm
(i)Tj
/F12 1 Tf
0.3958 0 TD
()Tj
/F13 1 Tf
0.7743 0 TD
(S)Tj
/F2 1 Tf
9.9626 0 0 9.9626 227.4 521.7271 Tm
(\()Tj
/F8 1 Tf
0.5059 0.6745 TD
(f)Tj
/F2 1 Tf
0.6023 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F13 1 Tf
6.9738 0 0 6.9738 248.4 527.007 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 251.64 528.447 Tm
(\))Tj
/F11 1 Tf
0.6143 0 TD
()Tj
/F2 1 Tf
1.2165 0.265 TD
()Tj
/F8 1 Tf
-0.2168 -0.265 TD
(f)Tj
/F2 1 Tf
0.6023 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F13 1 Tf
6.9738 0 0 6.9738 283.56 527.007 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 286.92 528.447 Tm
(\))Tj
ET
q
58.32 0 0 -0.48 232.428 524.475 cm
/Im3 Do
Q
BT
/F8 1 Tf
9.9626 0 0 9.9626 257.16 514.887 Tm
()Tj
/F13 1 Tf
6.9738 0 0 6.9738 262.8 513.447 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 291.96 521.7271 Tm
(\))Tj
/F3 1 Tf
6.9738 0 0 6.9738 295.8 525.807 Tm
(2)Tj
/F2 1 Tf
9.9626 0 0 9.9626 303.12 521.7271 Tm
(=)Tj
/F15 1 Tf
1.0479 0.9516 TD
()Tj
/F13 1 Tf
6.9738 0 0 6.9738 314.04 509.727 Tm
(i)Tj
/F12 1 Tf
0.3958 0 TD
()Tj
/F13 1 Tf
0.7743 0 TD
(S)Tj
/F2 1 Tf
9.9626 0 0 9.9626 327.96 521.7271 Tm
(\()Tj
/F8 1 Tf
0.5059 0.6745 TD
(f)Tj
/F2 1 Tf
0.6023 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F13 1 Tf
6.9738 0 0 6.9738 348.96 527.007 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 352.32 528.447 Tm
(\))Tj
/F11 1 Tf
0.6022 0 TD
()Tj
/F8 1 Tf
0.9997 0 TD
-0.0013 Tc
()Tj
/F2 1 Tf
1.3009 0 TD
0 Tc
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F13 1 Tf
6.9738 0 0 6.9738 391.32 527.007 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 394.56 528.447 Tm
(\))Tj
/F11 1 Tf
0.6143 0 TD
()Tj
/F8 1 Tf
0.9997 0 TD
()Tj
ET
q
83.76 0 0 -0.48 332.988 524.475 cm
/Im3 Do
Q
BT
9.9626 0 0 9.9626 370.44 514.887 Tm
()Tj
/F13 1 Tf
6.9738 0 0 6.9738 376.08 513.447 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 417.96 521.7271 Tm
(\))Tj
/F3 1 Tf
6.9738 0 0 6.9738 421.8 525.807 Tm
(2)Tj
/F2 1 Tf
9.9626 0 0 9.9626 462.84 521.7271 Tm
0.0059 Tc
[(\()9.3(13\))]TJ
-32.931 -3.3485 TD
0.0004 Tc
[(wher)-5.4(e)]TJ
/F8 1 Tf
2.8908 0 TD
0 Tc
()Tj
/F13 1 Tf
6.9738 0 0 6.9738 169.2 486.927 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 175.92 488.367 Tm
-0.0006 Tc
[(is)-328.9(lo)-30.6(ca)-6.5(l)-325.1(uncer)-6.4(ta)-6.5(in)25(t)26.9(y)-328(o)-6.5(f)-333.4(no)-6.5(r)-6.4(m)1.6(a)-6.5(lly)-316(distr)-6.4(i)0.1(buted)-336.4(er)-6.4(r)-6.4(o)-6.5(r)-319.6(\()]TJ
/F8 1 Tf
21.9702 0 TD
0 Tc
(f)Tj
/F2 1 Tf
0.6023 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F13 1 Tf
6.9738 0 0 6.9738 410.64 486.927 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 414 488.367 Tm
(\))Tj
/F11 1 Tf
0.6143 0 TD
()Tj
/F2 1 Tf
1.2165 0.265 TD
()Tj
/F8 1 Tf
-0.2168 -0.265 TD
(f)Tj
/F2 1 Tf
0.5902 0 TD
(\()Tj
/F9 1 Tf
0.3854 0 TD
(x)Tj
/F13 1 Tf
6.9738 0 0 6.9738 445.92 486.927 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 449.28 488.367 Tm
-0.0034 Tc
(\)\))Tj
/F3 1 Tf
6.9738 0 0 6.9738 456.96 491.967 Tm
0 Tc
(2)Tj
/F2 1 Tf
9.9626 0 0 9.9626 461.4 488.367 Tm
(.)Tj
-31.2809 -1.2045 TD
0.0058 Tc
[(P)23.9(a)-0.1(ram)8(e)4.6(t)9.2(e)4.6(rs)]TJ
/F8 1 Tf
5.2516 0 TD
0 Tc
()Tj
/F2 1 Tf
0.9756 0 TD
0.0059 Tc
[(an)7.4(d)]TJ
/F8 1 Tf
1.9272 0 TD
0 Tc
()Tj
/F2 1 Tf
0.9395 0 TD
0.0041 Tc
[(are)-298.2(e)2.9(st)7.5(i)4.8(m)6.3(at)7.5(ed)-319.6(b)29.7(y)-311.3(c)27(h)5.6(i)4.8(-)0.2(squ)5.6(a)-1.8(re)-298.2()5.6(t)7.5(t)7.5(i)4.8(n)5.6(g)-1.8(.)-320.4(S)5.6(i)4.8(n)5.6(ce)-322.3(b)-18.5(o)-1.8(t)7.5(h)-319.6(are)-298.2(n)5.6(on)5.6(-)]TJ
-10.5996 -1.1925 TD
[(n)5.6(e)2.9(gat)7.5(i)4.8(v)26(e,)-368.6(w)27.7(e)-382.6(i)4.8(n)29.7(t)7.5(r)-1.7(o)-25.9(d)5.6(u)5.6(c)2.9(e)-370.5(p)5.6(aram)6.3(et)7.5(ers)]TJ
/F8 1 Tf
15.5381 0 TD
0 Tc
(a)Tj
/F2 1 Tf
0.9154 0 TD
0.0059 Tc
[(an)7.4(d)]TJ
/F8 1 Tf
1.9995 0 TD
0 Tc
(b)Tj
/F2 1 Tf
0.8191 0 TD
0.0033 Tc
[(suc)26.2(h)-368.6(t)6.7(h)4.8(at)]TJ
/F8 1 Tf
4.5289 0 TD
0 Tc
()Tj
/F2 1 Tf
1.0118 0 TD
(=)Tj
/F8 1 Tf
1.1443 0 TD
(a)Tj
/F3 1 Tf
6.9738 0 0 6.9738 398.64 468.087 Tm
(2)Tj
/F2 1 Tf
9.9626 0 0 9.9626 406.92 464.487 Tm
0.0059 Tc
[(an)7.4(d)]TJ
/F8 1 Tf
1.9995 0 TD
0 Tc
()Tj
/F2 1 Tf
0.9877 0 TD
(=)Tj
/F8 1 Tf
1.1443 0 TD
(b)Tj
/F3 1 Tf
6.9738 0 0 6.9738 452.4 468.087 Tm
(2)Tj
/F2 1 Tf
9.9626 0 0 9.9626 456.84 464.487 Tm
0.3847 Tc
[(.T)384.2(h)386.2(e)]TJ
-32.3288 -1.2045 TD
-0.001 Tc
[(es)-4(tima)-6.9(tes)]TJ
/F8 1 Tf
4.3964 0 TD
0 Tc
()Tj
/F12 1 Tf
6.9738 0 0 6.9738 184.92 456.087 Tm
()Tj
/F2 1 Tf
9.9626 0 0 9.9626 192.96 452.487 Tm
0.0059 Tc
[(an)7.4(d)]TJ
/F8 1 Tf
1.9393 0 TD
0 Tc
()Tj
/F12 1 Tf
6.9738 0 0 6.9738 218.4 456.087 Tm
()Tj
/F2 1 Tf
9.9626 0 0 9.9626 226.32 452.487 Tm
0.0006 Tc
[(a)-5.3(r)-5.2(e)-325.8(g)-5.3(iv)22.5(en)-323.1(b)26.2(y)-326.8(so)-5.3(lving)]TJ
/F8 1 Tf
9.0338 0 TD
0.0593 Tc
()Tj
/F3 1 Tf
6.9738 0 0 6.9738 328.44 456.087 Tm
0 Tc
(2)Tj
/F8 1 Tf
9.9626 0 0 9.9626 332.88 452.487 Tm
0.0059 Tc
[(/)-53.4(a)]TJ
/F2 1 Tf
1.8911 0 TD
0.2822 Tc
[(=0)-48.9(a)276.3(n)283.7(d)]TJ
/F8 1 Tf
3.8424 0 TD
0.0593 Tc
()Tj
/F3 1 Tf
6.9738 0 0 6.9738 402.12 456.087 Tm
0 Tc
(2)Tj
/F8 1 Tf
9.9626 0 0 9.9626 406.56 452.487 Tm
0.0059 Tc
[(/)-53.4(b)]TJ
/F2 1 Tf
1.7827 0 TD
0.2822 Tc
[(=0)276.3(,)]TJ
-22.5723 -4.6735 TD
0 Tc
(\()Tj
/F8 1 Tf
0.3854 0 TD
()Tj
/F12 1 Tf
6.9738 0 0 6.9738 209.64 410.007 Tm
()Tj
/F8 1 Tf
9.9626 0 0 9.9626 214.32 405.927 Tm
0.1679 Tc
(,)Tj
/F12 1 Tf
6.9738 0 0 6.9738 224.88 410.007 Tm
0 Tc
()Tj
/F2 1 Tf
9.9626 0 0 9.9626 229.44 405.927 Tm
0.2856 Tc
(\)=)Tj
/F15 1 Tf
1.7224 3.2522 TD
0 Tc
()Tj
0 -0.9034 TD
()Tj
0 -0.3011 TD
()Tj
T*
()Tj
T*
()Tj
T*
( )Tj
0 -1.7947 TD
()Tj
0 -0.3011 TD
()Tj
T*
()Tj
T*
()Tj
T*
(\012)Tj
/F2 1 Tf
1.0359 4.3964 TD
(\()Tj
/F8 1 Tf
0.3854 0 TD
0.0028 Tc
[(p,)-165.1(q)]TJ
/F2 1 Tf
1.4334 0 TD
5.3325 Tc
[(\)i)5333.2(f)4999.7(p)]TJ
/F8 1 Tf
7.5281 0 TD
0 Tc
(>)Tj
/F2 1 Tf
1.1081 0 TD
0.3311 Tc
[(0a)325.2(n)332.6(d)7.4(q)]TJ
/F8 1 Tf
3.6376 0 TD
0 Tc
(>)Tj
/F2 1 Tf
1.1081 0 TD
(0)Tj
-15.2008 -1.6622 TD
(\()Tj
/F15 1 Tf
0.5059 1.3009 TD
()Tj
/F13 1 Tf
6.9738 0 0 6.9738 273.84 420.927 Tm
(f)Tj
/F3 1 Tf
0.6711 0 TD
(\()Tj
/F9 1 Tf
9.9626 0 0 9.9626 281.64 420.927 Tm
(x)Tj
/F17 1 Tf
4.9813 0 0 4.9813 287.64 419.967 Tm
(i)Tj
/F3 1 Tf
6.9738 0 0 6.9738 290.76 420.927 Tm
(\))Tj
/F13 1 Tf
0.4474 0 TD
()Tj
/F3 1 Tf
0.7743 0 TD
(\()Tj
/F9 1 Tf
9.9626 0 0 9.9626 302.4 420.927 Tm
(x)Tj
/F17 1 Tf
4.9813 0 0 4.9813 308.52 419.967 Tm
(i)Tj
/F3 1 Tf
6.9738 0 0 6.9738 311.64 420.927 Tm
(\))Tj
ET
q
52.8 0 0 -0.48 261.948 417.435 cm
/Im3 Do
Q
BT
/F15 1 Tf
9.9626 0 0 9.9626 270.12 416.487 Tm
()Tj
/F13 1 Tf
6.9738 0 0 6.9738 282 409.767 Tm
()Tj
/F3 1 Tf
0.7743 0 TD
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q
398.815 643.414 84.834 82.8 re
W n
0 842.013 595.008 -842.004 re
W n
0 G
0.109 w
403.808 648.571 m
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BT
/F10 1 Tf
3.9221 0 0 3.9221 409.6911 644.3039 Tm
0 Tc
(2)Tj
ET
424.744 648.571 m
424.744 649.352 l
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S
BT
3.9221 0 0 3.9221 423.6545 644.3039 Tm
(4)Tj
ET
438.707 648.571 m
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BT
3.9221 0 0 3.9221 437.618 644.3039 Tm
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ET
452.671 648.571 m
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BT
3.9221 0 0 3.9221 451.5814 644.3039 Tm
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ET
466.616 648.571 m
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BT
3.9221 0 0 3.9221 464.4372 644.3039 Tm
(10)Tj
ET
480.58 648.571 m
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BT
3.9221 0 0 3.9221 478.4006 644.3039 Tm
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ET
403.808 718.37 m
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BT
3.9221 0 0 3.9221 400.9935 716.9174 Tm
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ET
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BT
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ET
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BT
3.9221 0 0 3.9221 400.9935 689.0087 Tm
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ET
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BT
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ET
403.808 662.534 m
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BT
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ET
403.808 648.571 m
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BT
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S
EMC
Q
BT
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[(\(a)-3.5(\))-8228.8(\()1.9(b\))-8269(\(c\))-8255.6(\()1.9(d\))]TJ
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[(F)-8.6(i)-8.7(g.)-196.1(3.)]TJ
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3.4663 0 TD
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17.9071 0 TD
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[(nd)-352.6(\(b\))-349.9(illust)]TJ
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[(ra)7.7(te)-356.8(the)-343.4(g)7.7(ro)7.7(und-)-3(truth)-336.7(a)7.7(nd)]TJ
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/F6 1 Tf
22.7787 0 TD
0 Tc
()Tj
/F5 1 Tf
0.8565 0 TD
0.0032 Tc
[(=[)7.6(2)-299.3(-)-2.2(2)8.5(;)7.6(-2)-299.3(5)8.5(])-300.2(w)9.4(i)7.6(th)-309.1(ra)8.5(ndo)8.5(m)-304.7(a)8.5(ddi)7.6(ti)7.6(v)23.7(e)]TJ
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T*
-0.0043 Tc
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0 -1.2313 TD
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12.9552 0 TD
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-12.9552 -1.2179 TD
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/F2 1 Tf
9.9626 0 0 9.9626 134.76 524.007 Tm
0.0038 Tc
[(t)7.2(h)5.3(e)-274.5(m)6(axi)4.5(m)30.1(u)5.3(m)-259(of)-268.8(t)31.3(w)27.4(o)-255(s)0.8(u)5.3(p)-18.8(eri)4.5(m)6(p)-18.8(o)-2.1(sed)-271.8(1)-2.1(D)-256.1(G)5.6(au)5.3(ssi)4.5(an)5.3(s)-264.2(o)-2.1()9(s)0.8(et)-257.7(b)29.4(y)-263.4(a)-267.1(v)61.8(aryi)4.5(n)5.3(g)-267.1(d)5.3(i)4.5(st)7.3(an)5.3(ce)]TJ
/F8 1 Tf
33.5816 0 TD
0 Tc
(D)Tj
/F2 1 Tf
0.8552 0 TD
(.)Tj
-34.4368 -1.2045 TD
-0.0001 Tc
[(E)-6.1(a)-6(c)22.8(h)-239.5(Ga)-6(ussia)-6(n)-251.6(ha)-6(s)-256.1(t)3.3(he)-254.3(sa)-6(me)-254.3(v)57.9(a)-6(r)-5.9(i)0.6(a)-6(n)1.4(ce)]TJ
/F8 1 Tf
16.2608 0 TD
0 Tc
()Tj
/F2 1 Tf
0.8913 0 TD
0.2701 Tc
[(=1)11.3(a)264.2(n)271.6(d)6.6(h)271.6(i)270.8(g)264.2(h)295.7(t)]TJ
/F8 1 Tf
6.1912 0 TD
0 Tc
()Tj
/F2 1 Tf
0.9154 0 TD
0.0021 Tc
[(=)-280.1(1)-3.8(.)-250.1(T)1.6(he)-264.1(1D)-245.8(syst)5.5(em)-248.6(em)4.3(-)]TJ
-24.2587 -1.1925 TD
-0.0012 Tc
[(plo)17(y)-3.4(s)-341.5(a)-7.1(ll)-337.7(the)-351.7(a)17(v)56.8(a)-7.1(ila)-7.1(ble)-327.6(d)0.3(a)-7.1(t)2.2(a)-344.3(p)-23.8(o)-7.1(i)-0.5(n)24.4(t)2.3(s)-353.6(\()]TJ
/F8 1 Tf
15.5261 0 TD
0 Tc
(N)Tj
/F3 1 Tf
6.9738 0 0 6.9738 297.48 498.687 Tm
(1)Tj
/F2 1 Tf
9.9626 0 0 9.9626 304.92 500.127 Tm
(=)Tj
/F8 1 Tf
1.072 0 TD
(N)Tj
/F3 1 Tf
6.9738 0 0 6.9738 323.64 498.687 Tm
(2)Tj
/F2 1 Tf
9.9626 0 0 9.9626 331.08 500.127 Tm
(=)Tj
/F8 1 Tf
1.072 0 TD
(N)Tj
/F13 1 Tf
6.9738 0 0 6.9738 349.8 498.687 Tm
(S)Tj
/F2 1 Tf
9.9626 0 0 9.9626 355.56 500.127 Tm
0.0042 Tc
[(\))-341.7(a)-1.7(n)5.7(d)-331.6(40)-339(an)5.7(al)4.9(ysi)4.9(s)-324.1(scal)4.9(es)-324.1(w)3.7(i)4.9(t)7.6(h)]TJ
-22.1628 -1.2045 TD
0.0059 Tc
[(0.)6.6(05)-337.3(i)6.6(n)31.5(t)9.3(e)4.7(rv)63.9(al)-354.7(\()]TJ
/F8 1 Tf
6.1671 0 TD
0 Tc
(h)Tj
/F2 1 Tf
0.8913 0 TD
0.3183 Tc
[(=\()321.7(0)]TJ
/F8 1 Tf
1.9874 0 TD
0 Tc
(.)Tj
/F2 1 Tf
0.277 0 TD
(1)Tj
/F3 1 Tf
6.9738 0 0 6.9738 232.68 491.727 Tm
(2)Tj
/F8 1 Tf
9.9626 0 0 9.9626 237.12 488.127 Tm
(,)Tj
/F2 1 Tf
0.4457 0 TD
(0)Tj
/F8 1 Tf
0.5059 0 TD
(.)Tj
/F2 1 Tf
0.277 0 TD
0.0059 Tc
(15)Tj
/F3 1 Tf
6.9738 0 0 6.9738 259.44 491.727 Tm
0 Tc
(2)Tj
/F8 1 Tf
9.9626 0 0 9.9626 263.76 488.127 Tm
-0.0007 Tc
[(,)-168.6(..,)]TJ
/F2 1 Tf
1.4454 0 TD
0 Tc
(2)Tj
/F3 1 Tf
6.9738 0 0 6.9738 283.2 491.727 Tm
(2)Tj
/F2 1 Tf
9.9626 0 0 9.9626 287.52 488.127 Tm
0.3579 Tc
[(\)f)362.3(o)352(r)]TJ
/F9 1 Tf
2.3126 0 TD
0 Tc
(H)Tj
/F2 1 Tf
1.2165 0 TD
(=)Tj
/F8 1 Tf
1.0961 0 TD
(h)Tj
/F9 1 Tf
0.5782 0 TD
(I)Tj
/F2 1 Tf
0.4336 0 TD
0.0003 Tc
[(\).)-360.3(F)87(o)-5.6(r)-354.8(t)3.8(he)-362.3(sample)-362.3(v)58.3(a)-5.6(riance)-338.2(esti-)]TJ
-20.9704 -1.2045 TD
-0.001 Tc
[(ma)-6.9(tio)-6.9(n)0.5(,)-301.4(t)2.4(he)-303.3(densities)]TJ
/F8 1 Tf
9.371 0 TD
0 Tc
(p)Tj
/F2 1 Tf
0.5059 0 TD
(\()Tj
/F8 1 Tf
0.3854 0 TD
(x)Tj
/F13 1 Tf
6.9738 0 0 6.9738 242.64 474.687 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 246 476.127 Tm
-0.0007 Tc
[(\))-298.4(a)-6.6(r)-6.5(e)-291(a)-6.6(ppr)-6.5(o)17.5(x)-2.9(ima)-6.6(t)2.7(ed)-288.3(b)24.9(y)]TJ
/F8 1 Tf
9.9974 0 TD
0 Tc
(f)Tj
/F2 1 Tf
0.6023 0 TD
(\()Tj
/F8 1 Tf
0.3854 0 TD
(x)Tj
/F13 1 Tf
6.9738 0 0 6.9738 361.08 474.687 Tm
(i)Tj
/F2 1 Tf
9.9626 0 0 9.9626 364.44 476.127 Tm
0.0019 Tc
[(\))-295.8(n)3.4(ormalized)-285.7(b)27.5(y)-301.4(the)-300.4(p)3.4(roba-)]TJ
-23.0541 -1.1925 TD
-0.0012 Tc
[(bilit)26.3(y)-256.3(m)1(a)-7.1(s)-4.2(s)-233.1(w)-1.7(ithin)]TJ
/F11 1 Tf
7.9136 0 TD
0 Tc
()Tj
/F2 1 Tf
0.7829 0 TD
(1)Tj
/F8 1 Tf
0.5059 0 TD
()Tj
/F2 1 Tf
0.8432 0 TD
-0.0011 Tc
[(a)-7(r)-6.9(o)-7(und)-240.5(the)-255.3(t)2.3(r)-6.9(u)0.4(e)-243.2(m)1.1(a)-7(x)-3.3(im)25.2(um.)-241.3(T)-1.6(he)-255.3(r)-6.9(e)-2.3(sults)-245(i)-0.4(ndica)-7(ted)-240.5(t)2.3(ha)-7(t)-250.6(o)-7(ur)]TJ
-10.0456 -1.2045 TD
-0.0004 Tc
[(metho)-30.4(d)-324.1(a)-6.3(c)22.5(hiev)21.5(ed)-312.1(r)-6.2(o)-6.3(bust)-310.1(a)-6.3(nd)]TJ
12.6834 0 TD
-0.0012 Tc
[(a)-7.1(ccur)-7(a)-7.1(te)-315.6(es)-4.2(tima)-7.1(tio)-7.1(n)0.3(s)-317.4(e)-2.4(v)20.7(e)]TJ
10.6719 0 TD
0.0007 Tc
[(n)-311(w)0.2(ith)-323(t)4.1(he)-325.7(presence)-313.7(of)-320.1(the)]TJ
-23.3553 -1.2045 TD
0.0054 Tc
[(sev)27.3(e)4.2(re)-417.4(m)7.6(a)-0.5(rgi)6.1(n)6.9(-t)8.8(ru)6.9(n)6.9(c)4.2(at)8.9(i)6.1(o)-0.5(n)6.9(s)2.4(,)-403.4(c)4.2(l)6.1(e)4.2(arl)6.1(y)-418.4(d)6.9(e)4.2(m)7.6(o)-0.5(n)6.9(s)2.4(t)8.8(r)-0.4(at)8.8(i)6.1(n)6.9(g)-422.1(t)8.8(h)6.9(e)-429.4(ad)6.9(v)63.4(a)-0.5(n)31(t)8.8(age)-405.4(of)-423.8(ou)6.9(r)-434(f)9.8(ram)7.6(e)4.2(-)]TJ
0 -1.1925 TD
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[(w)23.1(o)-6.4(r)-6.3(k)-2.7(.)-361.1(F)1.8(ig)-6.4(.3)-379.8(sho)17.7(w)-1(s)-376.9(e)-1.7(xa)-6.4(mples)-376.9(w)-1(ith)-384.5(2)-6.4(D)-380.9(s)-3.5(yn)25.1(thetic)-387.2(da)-6.4(ta)-6.4(.)-373.2(E)-6.5(stima)-6.4(t)2.9(es,)-373.2(s)-3.5(ho)17.7(wn)-372.4(a)-6.4(s)-376.9(5)-6.4(0)-6.4(%)]TJ
0 -1.2045 TD
-0.0004 Tc
[(co)-6.3(ndence)-278.7(e)-1.6(llipses,)-276.7(b)25.2(y)-279.6(a)-283.3(2)-6.3(D)-272.4(i)0.3(mplemen)25.2(t)3(a)-6.3(t)3.1(io)-6.3(n)-275.9(o)-6.3(f)-285(o)-6.3(ur)-271.2(metho)-30.4(d)-288(a)-6.3(r)-6.2(e)-266.6(c)-1.6(o)-6.3(m)1.8(pa)-6.3(r)-6.2(e)-1.6(d)-263.9(f)4(o)-6.3(r)-283.3(t)27.1(w)23.2(o)]TJ
0 -1.1925 TD
[(t)27.2(y)-2.5(p)-22.9(e)-1.5(s)-304.5(o)-6.2(f)-309(t)3.1(est)-298(d)1.2(a)-6.2(t)3.1(a)-307.3(i)0.4(n)-299.9(t)3.1(he)-314.7(pr)-6.1(esence)-302.6(o)-6.2(f)-297(r)-6.1(a)-6.2(ndo)-6.2(m)-287.2(n)1.2(o)-6.2(i)0.4(se.)-300.7(T)-0.8(his)-304.5(2)-6.2(D)-296.4(i)0.4(mplemen)25.3(t)3.1(a)-6.2(t)3.1(io)-6.2(n)-312(u)1.2(ti-)]TJ
0 -1.2045 TD
0.0043 Tc
[(l)5(i)5(zes)-336(al)5(l)-332.2(a)22.5(v)62.3(a)-1.6(i)5(l)5(a)-1.6(b)5.8(l)5(e)-322.1(d)5.8(at)7.7(a)-338.9(p)-18.3(oi)5(n)29.9(t)7.7(s)-348(a)-1.6(n)5.8(d)-331.5(12)-326.8(an)5.8(al)5(ysi)5(s)-324(scal)5(es)-336(\()]TJ
/F8 1 Tf
23.259 0 TD
0 Tc
(h)Tj
/F2 1 Tf
0.8672 0 TD
0.2942 Tc
[(=\()297.6(0)]TJ
/F8 1 Tf
1.9633 0 TD
0 Tc
(.)Tj
/F2 1 Tf
0.277 0 TD
(5)Tj
/F3 1 Tf
6.9738 0 0 6.9738 402.48 396.087 Tm
(2)Tj
/F8 1 Tf
9.9626 0 0 9.9626 406.92 392.487 Tm
(,)Tj
/F2 1 Tf
0.4457 0 TD
(0)Tj
/F8 1 Tf
0.5059 0 TD
(.)Tj
/F2 1 Tf
0.277 0 TD
0.0059 Tc
(75)Tj
/F3 1 Tf
6.9738 0 0 6.9738 429.24 396.087 Tm
0 Tc
(2)Tj
/F8 1 Tf
9.9626 0 0 9.9626 433.56 392.487 Tm
-0.0007 Tc
[(,)-168.6(..,)]TJ
/F2 1 Tf
1.4454 0 TD
0 Tc
(3)Tj
/F8 1 Tf
0.5059 0 TD
(.)Tj
/F2 1 Tf
0.277 0 TD
0.0059 Tc
(25)Tj
/F3 1 Tf
6.9738 0 0 6.9738 465.84 396.087 Tm
0 Tc
(2)Tj
/F2 1 Tf
9.9626 0 0 9.9626 470.04 392.487 Tm
-0.0034 Tc
(\)\).)Tj
-33.6537 -1.2045 TD
-0.0012 Tc
[(The)-327.6(r)-7(esults)-329.5(a)-7.1(r)-7(e)-315.6(a)-7.1(lmo)-7.1(s)-4.2(t)-323(i)-0.5(den)24.4(t)2.2(ica)-7.1(l)-325.7(to)-332.3(the)-339.7(g)-7.1(r)-7(o)-7.1(und-)-5.1(tr)-7(uth)-312.9(d)0.3(espite)-327.6(the)-339.7(p)0.3(r)-7(e)-2.4(sence)-315.6(o)-7.1(f)-334(t)2.2(he)]TJ
0 -1.1925 TD
-0.0009 Tc
[(r)-6.7(a)-6.8(ndo)-6.8(m)-323.9(n)0.6(o)-6.8(i)-0.2(se)-327.3(a)-6.8(n)0.6(d)-324.6(t)2.5(he)-339.4(neig)-6.8(h)24.7(b)-23.5(o)-6.8(r)-6.7(ing)-320(s)-3.9(tr)-6.7(uctur)-6.7(e)-2.1(.)]TJ
/F9 1 Tf
0 -2.8185 TD
0.0002 Tc
[(4.)-5.6(2)-1147.2(L)5.3(ung)-388.4(HR)31.6(CT)-368.2(Data)]TJ
/F2 1 Tf
0 -1.8188 TD
0.0046 Tc
[(A)-221(3)-1.3(D)-219.2(i)5.3(m)6.8(p)6.1(l)5.3(e)3.4(m)6.8(e)3.4(n)30.2(t)8(at)8(i)5.3(o)-1.3(n)-222.8(o)-1.3(f)-219.8(t)8(h)6.1(e)-225.5(p)6.1(r)-1.2(op)-18(osed)-210.7(al)5.3(gori)5.3(t)8(h)6.1(m)-210(i)5.3(s)-227.3(ev)62.6(al)5.3(u)6.1(a)-1.3(t)8(e)3.4(d)-210.7(w)4.1(i)5.3(t)8(h)-234.8(h)6.1(i)5.3(g)-1.3(h)6.1(-)0.7(resol)5.3(u)6.1(t)8(i)5.3(on)]TJ
0 -1.1925 TD
[(com)6.8(p)6.1(u)6.1(t)8(ed)6.1(-t)8.1(om)6.8(ograp)6.1(h)30.2(y)-346.9(\()8(H)7.8(R)30.1(C)4.1(T)4.1(\))-377.4(i)5.3(m)6.8(ages)-359.8(o)-1.3(f)-364.4(p)6.1(u)6.1(l)5.3(m)6.8(o)-1.3(n)6.1(a)-1.3(ry)-359(t)8(u)6.1(m)6.8(o)-1.3(rs.)-368.1(E)-1.4(ac)27.5(h)-355.3(v)26.5(ol)5.3(u)6.1(m)6.8(et)8(ri)5.3(c)]TJ
0 -1.2045 TD
0.0049 Tc
[(i)5.6(m)7.1(age)-321.5(con)6.4(s)1.9(i)5.6(s)1.9(t)8.3(s)-323.4(of)-315.9(12-b)6.4(i)5.6(t)-316.9(p)-17.7(osi)5.6(t)8.3(i)5.6(v)26.8(e)-321.5(v)62.9(al)5.6(u)6.4(e)3.7(s)-323.4(o)23.1(v)26.8(e)3.7(r)-314.1(a)-1(n)-330.9(a)-1(rra)23.1(y)-298.4(o)-1(f)-315.9(512x512)-302.1(l)5.6(a)-1(t)8.3(t)8.3(i)5.6(ces.)]TJ
1.5056 -1.2045 TD
0.0046 Tc
[(A)-341.5(s)1.6(t)8(r)-1.2(ai)5.3(gh)30.2(t)8(f)9(orw)28.2(a)-1.3(rd)-295(i)5.3(m)6.8(p)6.1(l)5.3(em)6.8(en)30.2(t)8(a)-1.3(t)8(i)5.3(on)-343.2(of)-340.3(ou)6.1(r)-338.5(a)-1.3(l)5.3(gori)5.3(t)8(h)6.1(m)-318.4(w)4.1(i)5.3(t)8.1(h)6.1(ou)6.1(t)-341.3(a)-1.3(n)30.2(y)-334.9(3D)-339.7(sp)-18(eci)5.3()6.1(c)]TJ
-1.5056 -1.1925 TD
0.004 Tc
[(ad)5.5(ap)5.5(t)7.4(a)-1.9(t)7.4(i)4.7(on)-259.5(p)5.5(r)-1.8(o)22.2(v)1.8(i)4.7(d)5.5(es)-264(t)7.4(h)5.5(e)-286.3(3)-1.9(D)-268(t)7.4(u)5.5(m)6.2(or)-278.9(an)5.5(al)4.7(ysi)4.7(s)-264(syst)7.5(em)6.2(.)-272.3(A)-269.8(set)-281.6(o)-1.9(f)-268.6(a)-1.9(n)5.5(a)-1.9(l)4.7(y)1.8(si)4.7(s)-264(b)5.5(an)5.5(d)5.5(w)3.5(i)4.7(d)5.5(t)7.5(h)5.5(s)]TJ
0 -1.2045 TD
-0.0006 Tc
[(\(1)-6.5(8)-343.8(s)-3.6(ca)-6.5(les)-340.9(w)-1.1(ith)-348.4(0)-6.5(.2)-6.5(5)-331.7(i)0.1(n)25(t)2.8(er)-6.4(v)57.4(a)-6.5(l)]TJ
/F8 1 Tf
12.5871 0 TD
0 Tc
(h)Tj
/F2 1 Tf
0.8672 0 TD
0.3063 Tc
[(=\()309.8(0)]TJ
/F8 1 Tf
1.9754 0 TD
0 Tc
(.)Tj
/F2 1 Tf
0.277 0 TD
0.0059 Tc
(50)Tj
/F3 1 Tf
6.9738 0 0 6.9738 301.32 266.247 Tm
0 Tc
(2)Tj
/F8 1 Tf
9.9626 0 0 9.9626 305.64 262.647 Tm
(,)Tj
/F2 1 Tf
0.4457 0 TD
(0)Tj
/F8 1 Tf
0.5059 0 TD
(.)Tj
/F2 1 Tf
0.277 0 TD
0.0059 Tc
(75)Tj
/F3 1 Tf
6.9738 0 0 6.9738 327.96 266.247 Tm
0 Tc
(2)Tj
/F8 1 Tf
9.9626 0 0 9.9626 332.28 262.647 Tm
-0.0007 Tc
[(,)-168.6(..,)]TJ
/F2 1 Tf
1.4454 0 TD
0 Tc
(4)Tj
/F8 1 Tf
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(.)Tj
/F2 1 Tf
0.277 0 TD
0.0059 Tc
(75)Tj
/F3 1 Tf
6.9738 0 0 6.9738 364.56 266.247 Tm
0 Tc
(2)Tj
/F2 1 Tf
9.9626 0 0 9.9626 368.88 262.647 Tm
-0.0013 Tc
[(\)\))-347.2(a)-7.2(n)0.2(d)-337.1(m)0.9(a)-7.2(r)-7.1(k)20.6(e)-2.5(r)-7.1(s)-329.6(indica)-7.2(ting)]TJ
-23.4998 -1.2045 TD
0.0044 Tc
[(rou)5.9(g)-1.5(h)-379.6(t)7.8(u)5.9(m)6.6(or)-410.9(l)5.1(o)-25.6(cat)7.8(i)5.1(on)5.9(s)-384.1(a)-1.5(re)-394.3(gi)5.1(v)26.3(e)3.2(n)-391.6(t)7.8(o)-399(t)7.9(h)5.9(e)-406.4(syst)7.8(em)]TJ
/F14 1 Tf
21.1511 0 TD
0.4284 Tc
[(ap)433.6(r)428.5(i)433.9(o)433.6(r)428.5(i)]TJ
/F2 1 Tf
3.3967 0 TD
0.0013 Tc
[(.)-431.6(T)0.8(he)-397.4(mark)23.2(er)-390(lo)-28.7(cations)]TJ
-24.5478 -1.1925 TD
0.0043 Tc
[(are)-358.3(p)5.8(ro)22.5(vi)5(d)5.8(e)3.1(d)-343.5(b)29.9(y)-371.3(e)3.1(xp)-18.3(ert)-365.6(r)-1.5(ad)5.8(i)5(o)-1.6(l)5(ogi)5(st)7.7(s,)-332.2(h)5.8(o)22.5(w)27.9(e)3.1(v)26.2(e)3.1(r)-350.8(m)6.5(ost)-353.6(o)-1.6(f)-364.7(t)7.7(h)5.8(e)-370.3(m)6.5(a)-1.6(rk)26.2(ers)-348(d)5.8(evi)5(a)-1.6(t)7.7(e)-358.3(f)8.7(r)-1.5(om)]TJ
0 -1.2045 TD
-0.0006 Tc
[(the)-290.9(t)2.8(umo)-6.5(r)-295.5(cen)25(ter)-6.4(s)-280.7(with)-288.2(a)-283.5(cer)-6.4(ta)-6.5(in)-276.2(deg)-6.5(r)-6.4(ee.)-276.9(W)87.7(e)-290.9(use)-290.9(unifo)-6.5(r)-6.4(m)-287.5(sa)-6.5(mpling)-283.5(i)0.1(n)-288.2(t)2.8(he)-290.9(3)-6.5(-)-4.5(v)21.3(o)17.6(xel)]TJ
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275.861 680.016 m
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285.035 690.895 m
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279.524 696.801 m
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1 1 0 RG
0.568 w
273.114 694.117 m
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275.861 680.016 m
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BT
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ET
265.203 653.522 m
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BT
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ET
275.972 653.522 m
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BT
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ET
286.74 653.522 m
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BT
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ET
297.508 653.522 m
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BT
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ET
308.277 653.522 m
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BT
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ET
245.829 711.674 m
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BT
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ET
245.829 700.906 m
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BT
3.4105 0 0 3.4105 241.4874 699.6428 Tm
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ET
245.829 690.138 m
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BT
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ET
245.829 679.369 m
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BT
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ET
245.829 668.601 m
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BT
3.4105 0 0 3.4105 241.4874 667.3376 Tm
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ET
245.829 657.832 m
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BT
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ET
245.829 653.522 m
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312.587 720.28 m
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EMC
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Q
q
316.127 649.038 71.889 72 re
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0 842.013 595.008 -842.004 re
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1 g
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320.47 720.28 66.758 -66.758 re
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Q
q
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q
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316.127 649.038 71.889 72 re
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Q
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360.022 686.285 m
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q
316.127 649.038 71.889 72 re
W n
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0 G
0.095 w
320.47 653.522 m
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387.227 720.28 m
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320.47 720.28 m
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320.47 653.522 m
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320.47 720.28 m
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329.091 653.522 m
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BT
/F10 1 Tf
3.4105 0 0 3.4105 328.1432 649.8113 Tm
0 Tc
(5)Tj
ET
339.843 653.522 m
339.843 654.201 l
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S
BT
3.4105 0 0 3.4105 337.9485 649.8113 Tm
(10)Tj
ET
350.612 653.522 m
350.612 654.201 l
350.612 720.28 m
350.612 719.617 l
S
BT
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ET
361.38 653.522 m
361.38 654.201 l
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S
BT
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ET
372.148 653.522 m
372.148 654.201 l
372.148 720.28 m
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S
BT
3.4105 0 0 3.4105 370.2537 649.8113 Tm
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ET
382.917 653.522 m
382.917 654.201 l
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382.917 719.617 l
S
BT
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ET
320.47 711.674 m
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387.227 711.674 m
386.564 711.674 l
S
BT
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ET
320.47 700.906 m
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BT
3.4105 0 0 3.4105 316.1274 699.6428 Tm
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ET
320.47 690.138 m
321.133 690.138 l
387.227 690.138 m
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S
BT
3.4105 0 0 3.4105 316.1274 688.8744 Tm
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ET
320.47 679.369 m
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387.227 679.369 m
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BT
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ET
320.47 668.601 m
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BT
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ET
320.47 657.832 m
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S
BT
3.4105 0 0 3.4105 316.1274 656.5692 Tm
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ET
320.47 653.522 m
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320.47 720.28 m
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387.227 720.28 m
387.227 653.522 l
320.47 720.28 m
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S
EMC
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Q
q
390.767 649.038 71.889 72 re
W n
0 842.013 595.008 -842.004 re
W n
1 g
390.762 721.053 71.91 -72.018 re
f
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395.109 653.522 l
461.867 653.522 l
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395.109 720.28 l
S
Q
q
395.109 653.506 66.774 66.774 re
W n
q
68.9053 0 0 68.9053 394.0516 652.4481 cm
/Im9 Do
Q
Q
q
390.767 649.038 71.889 72 re
W n
0 842.013 595.008 -842.004 re
W n
0 0 1 RG
1.326 w
425.709 687.99 m
429.12 687.99 l
427.415 689.695 m
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BT
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ET
414.483 653.522 m
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BT
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BT
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BT
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BT
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EMC
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ET
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Q
q
245.829 578.266 66.774 66.774 re
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W n
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W n
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S
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S
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S
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S
1 1 0 RG
0.568 w
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S
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BT
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245.829 582.592 m
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W n
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320.47 645.04 m
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329.091 578.282 m
329.091 578.961 l
329.091 645.04 m
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BT
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ET
339.843 578.282 m
339.843 578.961 l
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BT
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ET
350.612 578.282 m
350.612 578.961 l
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BT
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ET
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361.38 578.961 l
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S
BT
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ET
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372.148 578.961 l
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BT
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ET
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382.917 578.961 l
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BT
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386.564 636.434 l
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BT
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ET
320.47 625.666 m
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BT
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ET
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BT
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ET
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BT
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ET
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BT
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ET
320.47 582.592 m
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387.227 582.592 m
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BT
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ET
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EMC
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S
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S
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1 1 0 RG
0.568 w
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S
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270.603 525.99 m
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S
279.177 521.68 m
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S
1 1 0 RG
0.568 w
285.508 526.701 m
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S
277.235 540.106 m
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S
270.603 525.99 m
270.572 526.069 l
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277.724 521.601 m
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S
279.177 521.68 m
279.082 521.68 l
278.924 521.648 l
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S
Q
q
241.487 498.438 71.889 72 re
W n
0 842.013 595.008 -842.004 re
W n
0 G
0.095 w
245.829 502.922 m
312.587 502.922 l
245.829 569.68 m
312.587 569.68 l
312.587 569.68 m
312.587 502.922 l
245.829 569.68 m
245.829 502.922 l
245.829 502.922 m
312.587 502.922 l
245.829 569.68 m
245.829 502.922 l
254.451 502.922 m
254.451 503.601 l
254.451 569.68 m
254.451 569.016 l
S
BT
/F10 1 Tf
3.4105 0 0 3.4105 253.5032 499.2112 Tm
0 Tc
(5)Tj
ET
265.203 502.922 m
265.203 503.601 l
265.203 569.68 m
265.203 569.016 l
S
BT
3.4105 0 0 3.4105 263.3084 499.2112 Tm
(10)Tj
ET
275.972 502.922 m
275.972 503.601 l
275.972 569.68 m
275.972 569.016 l
S
BT
3.4105 0 0 3.4105 274.0769 499.2112 Tm
(15)Tj
ET
286.74 502.922 m
286.74 503.601 l
286.74 569.68 m
286.74 569.016 l
S
BT
3.4105 0 0 3.4105 284.8453 499.2112 Tm
(20)Tj
ET
297.508 502.922 m
297.508 503.601 l
297.508 569.68 m
297.508 569.016 l
S
BT
3.4105 0 0 3.4105 295.6137 499.2112 Tm
(25)Tj
ET
308.277 502.922 m
308.277 503.601 l
308.277 569.68 m
308.277 569.016 l
S
BT
3.4105 0 0 3.4105 306.3821 499.2112 Tm
(30)Tj
ET
245.829 561.074 m
246.493 561.074 l
312.587 561.074 m
311.924 561.074 l
S
BT
3.4105 0 0 3.4105 243.3821 559.8112 Tm
(5)Tj
ET
245.829 550.306 m
246.493 550.306 l
312.587 550.306 m
311.924 550.306 l
S
BT
3.4105 0 0 3.4105 241.4874 549.0428 Tm
(10)Tj
ET
245.829 539.538 m
246.493 539.538 l
312.587 539.538 m
311.924 539.538 l
S
BT
3.4105 0 0 3.4105 241.4874 538.2744 Tm
(15)Tj
ET
245.829 528.769 m
246.493 528.769 l
312.587 528.769 m
311.924 528.769 l
S
BT
3.4105 0 0 3.4105 241.4874 527.506 Tm
(20)Tj
ET
245.829 518.001 m
246.493 518.001 l
312.587 518.001 m
311.924 518.001 l
S
BT
3.4105 0 0 3.4105 241.4874 516.7375 Tm
(25)Tj
ET
245.829 507.232 m
246.493 507.232 l
312.587 507.232 m
311.924 507.232 l
S
BT
3.4105 0 0 3.4105 241.4874 505.9691 Tm
(30)Tj
ET
245.829 502.922 m
312.587 502.922 l
245.829 569.68 m
312.587 569.68 l
312.587 569.68 m
312.587 502.922 l
245.829 569.68 m
245.829 502.922 l
S
EMC
/EmbeddedDocument /MC23 BDC
Q
q
316.127 498.438 71.889 72 re
W n
0 842.013 595.008 -842.004 re
W n
1 g
316.116 570.447 71.91 -72.018 re
f
320.47 569.68 66.758 -66.758 re
f
1 G
0.095 w
320.47 569.68 m
320.47 502.922 l
387.227 502.922 l
387.227 569.68 l
320.469 569.68 l
S
Q
q
320.47 502.906 66.774 66.774 re
W n
q
68.9053 0 0 68.9053 319.4116 501.8481 cm
/Im15 Do
Q
Q
q
316.127 498.438 71.889 72 re
W n
0 842.013 595.008 -842.004 re
W n
0 0 1 RG
1.326 w
351.07 537.39 m
354.48 537.39 l
352.775 539.095 m
352.775 535.685 l
S
1 1 0 RG
0.568 w
351.259 537.39 m
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352.775 538.906 m
352.775 535.874 l
S
0 0 1 RG
1.326 w
353.564 536.553 m
356.217 533.901 l
356.217 536.553 m
353.564 533.901 l
S
1 1 0 RG
0.568 w
353.691 536.427 m
356.091 534.027 l
356.091 536.427 m
353.691 534.027 l
S
Q
0 0 1 RG
1.326 w
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S
346.27 539.048 m
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S
356.517 528.153 m
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S
363.796 532.053 m
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S
1 1 0 RG
0.568 w
361.112 539.159 m
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S
346.27 539.048 m
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0.095 w
320.47 502.922 m
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BT
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ET
339.843 502.922 m
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BT
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ET
350.612 502.922 m
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BT
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(15)Tj
ET
361.38 502.922 m
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BT
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ET
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BT
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ET
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S
BT
3.4105 0 0 3.4105 381.0221 499.2112 Tm
(30)Tj
ET
320.47 561.074 m
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BT
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ET
320.47 550.306 m
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BT
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ET
320.47 539.538 m
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BT
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ET
320.47 528.769 m
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BT
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ET
320.47 518.001 m
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BT
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ET
320.47 507.232 m
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BT
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ET
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390.767 498.438 71.889 72 re
W n
0 842.013 595.008 -842.004 re
W n
1 g
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Q
q
395.109 502.906 66.774 66.774 re
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q
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S
191.994 453.014 m
191.962 453.093 l
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S
207.799 448.53 m
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S
211.336 459.378 m
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S
1 1 0 RG
0.568 w
204.483 464.809 m
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S
191.994 453.014 m
191.962 453.093 l
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S
207.799 448.53 m
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430.209 453.82 m
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S
Q
q
395.109 416.746 66.774 66.774 re
W n
390.767 412.278 71.889 72 re
W n
0 842.013 595.008 -842.004 re
W n
0 0 1 RG
1.326 w
432.42 453.299 m
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S
426.609 455.778 m
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S
428.204 449.083 m
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S
1 1 0 RG
0.568 w
432.42 453.299 m
432.436 453.267 l
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S
426.609 455.778 m
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S
428.204 449.083 m
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280.535 393.081 m
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S
275.545 398.781 m
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S
1 1 0 RG
0.568 w
270.082 394.675 m
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S
273.493 378.365 m
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S
280.535 393.081 m
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276.098 398.718 m
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S
275.545 398.781 m
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S
Q
q
241.487 336.918 71.889 72 re
W n
0 842.013 595.008 -842.004 re
W n
0 G
0.095 w
245.829 341.402 m
312.587 341.402 l
245.829 408.16 m
312.587 408.16 l
312.587 408.16 m
312.587 341.402 l
245.829 408.16 m
245.829 341.402 l
245.829 341.402 m
312.587 341.402 l
245.829 408.16 m
245.829 341.402 l
254.451 341.402 m
254.451 342.081 l
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S
BT
/F10 1 Tf
3.4105 0 0 3.4105 253.5032 337.6912 Tm
0 Tc
(5)Tj
ET
265.203 341.402 m
265.203 342.081 l
265.203 408.16 m
265.203 407.496 l
S
BT
3.4105 0 0 3.4105 263.3084 337.6912 Tm
(10)Tj
ET
275.972 341.402 m
275.972 342.081 l
275.972 408.16 m
275.972 407.496 l
S
BT
3.4105 0 0 3.4105 274.0769 337.6912 Tm
(15)Tj
ET
286.74 341.402 m
286.74 342.081 l
286.74 408.16 m
286.74 407.496 l
S
BT
3.4105 0 0 3.4105 284.8453 337.6912 Tm
(20)Tj
ET
297.508 341.402 m
297.508 342.081 l
297.508 408.16 m
297.508 407.496 l
S
BT
3.4105 0 0 3.4105 295.6137 337.6912 Tm
(25)Tj
ET
308.277 341.402 m
308.277 342.081 l
308.277 408.16 m
308.277 407.496 l
S
BT
3.4105 0 0 3.4105 306.3821 337.6912 Tm
(30)Tj
ET
245.829 399.554 m
246.493 399.554 l
312.587 399.554 m
311.924 399.554 l
S
BT
3.4105 0 0 3.4105 243.3821 398.2912 Tm
(5)Tj
ET
245.829 388.786 m
246.493 388.786 l
312.587 388.786 m
311.924 388.786 l
S
BT
3.4105 0 0 3.4105 241.4874 387.5228 Tm
(10)Tj
ET
245.829 378.018 m
246.493 378.018 l
312.587 378.018 m
311.924 378.018 l
S
BT
3.4105 0 0 3.4105 241.4874 376.7544 Tm
(15)Tj
ET
245.829 367.249 m
246.493 367.249 l
312.587 367.249 m
311.924 367.249 l
S
BT
3.4105 0 0 3.4105 241.4874 365.986 Tm
(20)Tj
ET
245.829 356.481 m
246.493 356.481 l
312.587 356.481 m
311.924 356.481 l
S
BT
3.4105 0 0 3.4105 241.4874 355.2175 Tm
(25)Tj
ET
245.829 345.712 m
246.493 345.712 l
312.587 345.712 m
311.924 345.712 l
S
BT
3.4105 0 0 3.4105 241.4874 344.4491 Tm
(30)Tj
ET
245.829 341.402 m
312.587 341.402 l
245.829 408.16 m
312.587 408.16 l
312.587 408.16 m
312.587 341.402 l
245.829 408.16 m
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S
EMC
/EmbeddedDocument /MC31 BDC
Q
q
316.127 336.918 71.889 72 re
W n
0 842.013 595.008 -842.004 re
W n
1 g
316.116 408.933 71.91 -72.018 re
f
320.47 408.16 66.758 -66.758 re
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1 G
0.095 w
320.47 408.16 m
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S
Q
q
320.47 341.386 66.774 66.774 re
W n
q
68.9053 0 0 68.9053 319.4116 340.3281 cm
/Im23 Do
Q
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S
348.054 386.733 m
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1 1 0 RG
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S
208.446 302.193 m
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S
201.546 310.893 m
201.641 310.862 l
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S
1 1 0 RG
0.568 w
193.131 308.02 m
193.194 308.099 l
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190.036 297.567 m
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S
195.736 290.335 m
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204.531 292.23 m
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196.178 290.178 l
196.099 290.209 l
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S
208.446 302.193 m
208.446 302.083 l
208.462 301.988 l
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203.536 310.167 m
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S
201.546 310.893 m
201.641 310.862 l
201.72 310.846 l
201.815 310.814 l
201.909 310.799 l
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203.536 310.167 l
S
q
166.967 261.678 71.889 72 re
W n
0 842.013 595.008 -842.004 re
W n
0 G
0.095 w
171.309 266.162 m
238.067 266.162 l
171.309 332.92 m
238.067 332.92 l
238.067 332.92 m
238.067 266.162 l
171.309 332.92 m
171.309 266.162 l
171.309 266.162 m
238.067 266.162 l
171.309 332.92 m
171.309 266.162 l
179.931 266.162 m
179.931 266.841 l
179.931 332.92 m
179.931 332.256 l
S
BT
/F10 1 Tf
3.4105 0 0 3.4105 178.9832 262.4512 Tm
0 Tc
(5)Tj
ET
190.683 266.162 m
190.683 266.841 l
190.683 332.92 m
190.683 332.256 l
S
BT
3.4105 0 0 3.4105 188.7884 262.4512 Tm
(10)Tj
ET
201.452 266.162 m
201.452 266.841 l
201.452 332.92 m
201.452 332.256 l
S
BT
3.4105 0 0 3.4105 199.5569 262.4512 Tm
(15)Tj
ET
212.22 266.162 m
212.22 266.841 l
212.22 332.92 m
212.22 332.256 l
S
BT
3.4105 0 0 3.4105 210.3253 262.4512 Tm
(20)Tj
ET
222.988 266.162 m
222.988 266.841 l
222.988 332.92 m
222.988 332.256 l
S
BT
3.4105 0 0 3.4105 221.0937 262.4512 Tm
(25)Tj
ET
233.757 266.162 m
233.757 266.841 l
233.757 332.92 m
233.757 332.256 l
S
BT
3.4105 0 0 3.4105 231.8621 262.4512 Tm
(30)Tj
ET
171.309 324.314 m
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238.067 324.314 m
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S
BT
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(5)Tj
ET
171.309 313.546 m
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238.067 313.546 m
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S
BT
3.4105 0 0 3.4105 166.9674 312.2828 Tm
(10)Tj
ET
171.309 302.778 m
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S
BT
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(15)Tj
ET
171.309 292.009 m
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S
BT
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(20)Tj
ET
171.309 281.241 m
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237.404 281.241 l
S
BT
3.4105 0 0 3.4105 166.9674 279.9775 Tm
(25)Tj
ET
171.309 270.472 m
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238.067 270.472 m
237.404 270.472 l
S
BT
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(30)Tj
ET
171.309 266.162 m
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238.067 332.92 m
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S
EMC
/EmbeddedDocument /MC34 BDC
Q
q
241.487 261.678 71.889 72 re
W n
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W n
1 g
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f
245.829 266.162 66.758 66.758 re
f*
1 G
0.095 w
245.829 332.92 m
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312.587 266.162 l
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Q
q
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W n
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W n
0 842.013 595.008 -842.004 re
W n
q
68.9053 0 0 68.9053 244.7716 265.088 cm
/Im26 Do
Q
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q
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Q
q
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W n
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W n
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277.235 323.509 m
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275.687 307.262 m
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S
282.477 303.267 m
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S
1 1 0 RG
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277.235 323.509 m
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W n
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BT
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BT
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q
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S
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S
429.72 307.088 m
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S
1 1 0 RG
0.568 w
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S
423.815 298.751 m
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S
429.72 307.088 m
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